antidepressant相关论文
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Antidepressant-like effects and memory enhancement of a herbal formula in mice exposed to chronic mi
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The Current Situation on Major Depressive Disorder in China: Research on Mechanisms and Clinical Pra
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Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania
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Intervention of Mirtazapine on gemcitabine-induced mild cachexia in nude mice with pancreatic carcin
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目的 通过分析抑郁症患者大脑静息态功能网络拓扑属性特征,寻找可以预测抗抑郁剂早期疗效的敏感指标。方法 入组82例抑郁症患者和5......
Loss of Phenotype of Parvalbumin Interneurons Contrib utes to the Antidepressant Effects of Ketamine
Depression is a highly prevalent disorder and currently available antidepressants have delayed onset of actions with low......
Timosaponin from Chinese herb Rhizoma anemarrhenae has been indicated to have essential effect in both clinical depressi......
Neuropsychopharmacology of ketamine as a rapid-acting agent on depression and suicidal ideation in d
Ketamine is classified as a dissociative anesthetic agent for anesthesia and pain control,and used as an experimental to......
Citalopram, a selective serotonin reuptake inhibitor (SSRI), as well as an antidepressant, is thought to exert its effec......
Antidepressant, anxiolytic and anti-PTSD effects of YL-IPA08, a potent ligand for the translocator p
Aim: The translacator protein (18 kDa) (TSPO), previously called peripheral bernzodiazepine receptor, is the key element......
Aim YL0919 is permitted by SFDA for clinical trial recendy as a new drug for depression.Whether YL0919 is a fastonset an......
Paeoniflorin (PF) is the major bioactive constituent of peony root, which has been used to treat depressive patients in ......
RNA interference-mediated phosphodiesterase-4D knockdown in the prefrontal cortex elicits antidepres
OBJECTIVE Phosphodiesterase 4 (PDE4), specific for cyclic AMP (cAMP)-hydrolyzing, has four isoforms (PDE4A-D) with at le......
OBJECTIVE To establish recombinant human monoamine neurotransmitter including serotonin, norepinephrine, dopamine transp......
Antidepressant drug citalopram inhibits delayed rectifier outward K+ current in mouse cortical neuro
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Growing evidence has implicated glial anomalies in the pathophysiology of major depression disorder (MDD).Gap junctional......
OBJECTIVE Fructus Akebiae (FAE) is a tradi tional Chinese herbal that has been used for the treatment of de pressive dis......
Immuno-regulatory Dectin-1 Mediates a Fast-acting Antidepressant Effect by Enhancing the Prefrontal/
It is well-established that neuroimmunity is involved in the pathophysiology and treatment of mood disorders.Dectin-1 is......
Irritable bowel syndrome (IBS), a well-known chronic functional gastrointestinal (GI) disorder, is a psychiatric comorbi......
Ethnopharmacological relevance: Xiaoyaosan (XYS) is a famous traditional Chinese medicine prescription with a long histo......
Network Pharmacology-based Research of Active Components of Albiziae Flos and Mechanisms of Its Anti
Albiziae Flos(AF)has been experimentally proven to have an antidepressant effect.However,due to the complexity of botani......
目的观察白藜芦醇(RES)对脊髓损伤(SCI)小鼠炎性反应和抑郁情绪的影响。方法采用改良的Allen’s击打法制作SCI小鼠模型，采用随机数......
Combination of Geniposide and Eleutheroside B Exerts Antidepressant-like Effect on Lipopolysaccharid
Objective To study the antidepressant-like effect and action mechanism of geniposide and eleutheroside B combination tre......
OBJECTIVE Sigma-1 receptors are involved in the pathophysiological process of several neuropsychiatric diseases such......
Antidepressant-like effects of Ginsniside Rb1 through pro-neurogenesis by regulating the microenviro
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Regulation of mTORC1 signaling network underlying the pathophysiology and treatment of depression ne
Depression is a devastating mental disorder and major depressive disorder afflictsabout 16% of the world population ......
Given the failure to develop disease-modifying therapies for Alzheimer’s disease (AD), strategies aiming at preventing ......
目的 探讨3种不同类型抗抑郁药对脑源性神经营养因子(BDNF)、神经营养因子3(NT-3)及其功能性受体TrkB/C在抗抑郁效应及抑郁症病理......
目的 探讨脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)Val66Met功能基因多态性和环境因素及其相互作用对抗抑郁......
非编码RNA(ncRNA)主要包括微小RNA (microRNA，miRNA)、长链非编码RNA(long non-coding RNA，lncRNA)以及环状RNA(circular RNA，circRNA......
中国全科医学杂志与澳大利亚Monash大学和Melbourne大学的全科医学专家和心理学专家在2012年伊始共同推出“全科医学中的心理健康......
抑郁症是一种常见的精神疾病.目前的抗抑郁药主要是通过增加突触间隙单胺类的5-羟色胺和去甲肾上腺素水平来发挥作用.近年来国内外......
目前精神疾病的病因尚未完全明了,一旦确诊则需要长期甚至终生服药治疗,尤其是精神分裂症及抑郁症这两种精神科常见疾病.抗精神病......
抗抑郁药除了具有抗抑郁及抗焦虑的临床治疗作用外，同样具有不良反应。抗抑郁药物的不良反应一般可分为中枢性不良反应和外周性不良......
Neuropharmacological evaluation of methanolic extract of Costus speciosus Linn. rhizome in Swiss alb
Objective: To evaluate the neuropharmacological properties of Costus speciosus (C. speciosus) rhizome using different ex......
目的:对临床上使用的及临床试验中的抗抑郁药物进行分析和总结,拟为今后新型抗抑郁药物的研发提供参考。方法:通过查阅近年的文献,......
Pre-concentration and determination of amitriptyline residues in waste water by ionic liquid based i
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目的：分析抗抑郁药物联合疏肝调神针法对老年脑卒中后抑郁症患者生活质量的影响。方法：88例老年脑卒中后抑郁症患者随机分成治疗组和......
目的:探讨异黄酮类中药单体大豆黄素对慢性不可预见性应激抑郁模型大鼠行为的影响及可能的机制。方法:将50只雄性大鼠按随机数字表......
制备姜黄素二癸酸酯,并对其药理长效性进行研究。姜黄素与癸酰氯发生酯化后形成姜黄素二癸酸酯(Curcumin didecanoate,CDD),将CDD......
Agmatine increases proliferation of cultured hippocampal progenitor cells and hippocampal neurogenes
Aim:To explore the mechanism of agmatine’s antidepressant action.Methods: Male mice were subjected to a variety of unpr......
